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What Is alopecia areata?

pattern baldness is considered an autoimmune disease, in which the immune system, which is designed to protect the body from foreign invaders such as viruses and bacteria, mistakenly attacks the hair follicles, the tiny cup-shaped stopped from which hairs grow, alopecia androgenetic female. This can lead to baldness on the scalp and other sites on the body.

In most cases, hair falls out in tiny, round patches about the size of a dime. In many situations, the affliction does not extend beyond a couple of patches. In some individuals, loss of hair is more extensive. Although uncommon, alopecia androgenetic female, the ailment can carry on to to cause total loss of hair on the head (referred to as alopecia totalis) or complete loss of hair on the head, face, and body (alopecia universalis).

What Causes It?

In male or female pattern baldness, immune system cells called white blood cells attack the rapidly growing cells in the hair follicles that make the hair. The problem hair follicles become small and radically impede hair production. Fortunately, the stem cells that continually supply the follicle with new cells do not seem to be targeted. Therefore the follicle always has the potential to regrow hair - alopecia androgenetic female.

Scientists do not know exactly why the hair follicles undergo these changes, alopecia androgenetic female but they are fairly certain that a combination of genes may predispose some people to the condition. In those who are genetically predisposed, some type of trigger - perhaps a virus or something in the person's environment - brings on the assault against the hair follicles.

Who Is Most Likely To Get It?

pattern baldness seriously affects around 4 million citizens of the United States of both sexes and of all ages and ethnic backgrounds. It often begins in childhood alopecia androgenetic female.

If you are unfortunate enough to have a close family member with the disease, your risk of developing it is slightly increased. If your relative lost her or his initial patch of hair before their early thirties, the risk to other relations is greater. Generally speaking, one in five folks that are afflicted with the affliction have a family member who has it too.

Is My male or female pattern baldness a Symptom of a Serious Disease?

alopecia areata is not a life-threatening ailment and neither is alopecia androgenetic female. It does not instigates any physical pain, and persons with the ailment are generally healthy otherwise. But for most people, a condition that unpredictably affects their appearance the way male or female pattern baldness does is a serious matter.

The effects of alopecia areata are primarily socially and emotionally worrying. In alopecia universalis, however, loss of eyelashes and eyebrows and hair in the nose and ears can make the person more susceptible to dust, germs, and foreign particles entering the nose, eyes, and ears.

pattern baldness often occurs in citizens whose relatives have other autoimmune diseases, such as diabetes, rheumatoid arthritis, systemic lupus erythematosus, pernicious anemia, thyroid disease or Addison's disease or even alopecia androgenetic female. People who have pattern baldness do not typically have other autoimmune diseases, but they do tend to have a higher occurrence of asthma, atopic eczema, thyroid disease and nasal allergies, alopecia androgenetic female.

Can I Pass It on to My Children?

It is possible, but not likely, for alopecia areata to be inherited. Most children with male or female pattern baldness do not have a father or mother with the disease, and the vast majority of parents with alopecia areata do not pass it along to their children.

pattern baldness is not like some genetic conditions in which a child has a 50 50 chance of developing the ailment if one parent has it. Hair research scientists believe that there may be a number of genes that predispose certain people to the affliction. It is highly unlikely that a child would inherit all of the genes required to predispose him or her to the disease.

Even with the right (or wrong) combination of genes, male or female pattern baldness is not a certainty. In identical twins, who share all of the same genes, the concordance rate is only fifty five percent. In other words, if one twin has the ailment, there is only a 55 percent chance that the other twin will have it also. This shows that other considerations besides genetics are required to trigger the affliction.

To learn more with regard to the genes and other factors involved in alopecia areata risk, the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is funding an male or female pattern baldness registry alopecia androgenetic female. The registry is a controlled network of five centers throughout the USA that will identify and register patients that are affected by the condition and collect data and blood samples (which contain genes). Data, including genetic information, will be made available to researchers investigating the genetic origin and other aspects of disease and disease risk. (For more information with reference to the registry, see "How Can I Take Part In Research?")

Will My Hair Ever Grow Back?

There is an extremely good chance that your hair will grow back, but it might also fall out again however. It's impossible to predict when it might regrow or fall out. The course of the affliction varies from person to person. Some folks lose just a few patches of hair, alopecia androgenetic female after which the hair grows again and the condition never recurs. Other citizens continue to lose and regrow hair for many years. Some individuals lose all the hair on their head, face and body; whilst others lose all the hair on their head. Even in those who suffer from total hair loss, the possibility for full regrowth remains. In some, the initial hair re-growth is white, with a gradual return of the original hair color. In most, the regrown hair is in the end the same color and texture as the original hair.

What Can I Expect Next?

The course of pattern baldness is highly unpredictable, and the uncertainty of what will happen next is probably the hardest and most frustrating effect of the disease. You may continue to lose hair, or your hair loss may stop, alopecia androgenetic female. Your lost hair could grow back but it may not and you may or may not continue to develop new bare patches.

How Is It Treated?

[While there is neither a cure for alopecia areata nor drugs approved for its treatment], some persons find that medicines approved for other purposes like male or female pattern baldness can help hair grow back, alopecia androgenetic female at least temporarily. The following are some methods of treatment for pattern baldness. Keep in mind that while these treatments may promote hair growth, none of them prevent new patches or actually cure the underlying condition. Consult your health care professional with reference to the best option for you.

  • Corticosteroids - Corticosteroids are powerful anti-inflammatory drugs, alopecia androgenetic female, similar to a hormone known as cortisol produced in the body. Because these drugs suppress the immune system if given orally, they are often used in the treatment of various autoimmune diseases, including alopecia androgenetic female. Corticosteroids may be applied in three ways for alopecia areata:

  • Local injections - Injections of steroids directly into hairless patches on the scalp and occasionally the brow and beard areas are effective in hair growth in most individuals. It habitually takes about one month for new hair growth to become visible. Injections deliver tiny amounts of cortisone to affected areas, avoiding the more serious side effects encountered with long-term oral use. The main side effects of innoculations are transient pain, mild swelling, and sometimes changes in pigmentation, as well as small indentations in the skin that go away when innoculations are halted. Because injections can be painful, they may not be the preferred treatment for children. After 4 to 8 weeks, new hair growth customarily becomes visible, and the innoculations ordinarily have to be repeated monthly. The cortisone takes out the confused immune cells and allows the hair to grow. Large areas cannot be treated, however, because the discomfort and the quantity of medicine become too great and can result in side effects similar to those of the oral regimen.

  • Oral corticosteroids - Corticosteroids taken orally are a mainstay of treatment for many autoimmune diseases and may be used in more extensive pattern baldness. But because of the risk of side effects of oral corticosteroids, such as hypertension, alopecia androgenetic female and cataracts, they are used only occasionally for alopecia areata and for shorter periods of time.

  • Topical ointments - ointments or creams containing steroids rubbed directly onto the affected area are less traumatic than injections and, therefore, are occasionally preferred for children. However, corticosteroid ointments and creams alone are less effective than innoculations; they work best when combined with other topical methods of treatment, such as minoxidil or anthralin.

  • Minoxidil (5%) (Rogaine) - Topical minoxidil mixture promotes hair growth in several conditions in which the hair follicle is tiny and not growing to its full potential. Minoxidil is FDA-approved for treating male and female pattern alopecia. It may also be useful in promoting hair growth in male or female pattern baldness. The tincture, applied twice daily, has been shown to promote hair growth in both adults and children, and may be used on the scalp, brow, and beard areas. With constant and proper use of the solution, new hair growth appears in with reference to three months.

  • Brand names included in this article are provided as examples only, and their inclusion does not mean that these products are endorsed by the National Institutes of Health or any other Government agency. Also, if a particular brand name is not mentioned, this does not mean or imply that the product is not worthwhile.

  • Anthralin (Psoriatec) - Anthralin, a man-made tar-like substance that alters immune function in the problem skin, is an approved treatment for psoriasis. Anthralin is also commonly used to treat male or female pattern baldness. Anthralin is applied for one to three hours ("short contact therapy") to help avoid skin irritation, alopecia androgenetic female which is not necessary for the drug to work. When it works, new hair growth is by and large self evident in two to three months. Anthralin is often used in combination with other treatments, such as corticosteroid injections or minoxidil, for improved results.

  • Sulfasalazine - A sulfa drug, sulfasalazine has been used as a treatment for different autoimmune disorders, including psoriasis. It acts on the immune system and has been used to some effect in patients with severe pattern baldness.

  • Topical sensitizers - Topical sensitizers are medications that, when applied to the scalp, instigate an allergic reaction that leads to itching, scaling, and eventually hair growth. If the medication works, new hair growth is commonly established in three to twelve months. Two topical sensitizers are used in alopecia areata: squaric acid dibutyl ester (SADBE) and diphenylcyclopropenone (DPCP). Their safety and consistency of formula are currently under review.

  • Oral cyclosporine - Originally developed to keep citizens's immune systems from rejecting transplanted organs, oral cyclosporine is sometimes used to suppress the immune system response in psoriasis and other immune-mediated skin conditions. But suppressing the immune system can also instigates problems, including an increased risk of serious infection and possibly skin cancer. Although oral cyclosporine may regrow hair in male or female pattern baldness, it does not turn the ailment off. Most MDs feel the dangers of the drug outweigh its benefits for pattern baldness and alopecia androgenetic female.

  • Photochemotherapy - In photochemotherapy, a treatment used most commonly for psoriasis, a person is given a light-sensitive drug known as a psoralen either orally or topically given and then exposed to an ultraviolet light source. This combined treatment is called PUVA. In clinical trials, an estimated fifty five percent of folks achieve cosmetically acceptable hair growth using photochemotherapy. However, the relapse rate is high, and patients must go to a treatment center where the equipment is available at least two to three times per week. Furthermore, the treatment sustains the risk of developing skin cancer.

  • Alternative therapies - When drug treatments fail to bring acceptable hair re-growth, some people turn to alternative therapies - alopecia androgenetic female. Alternatives purported to help alopecia areata include acupuncture, Chinese herbs, zinc and vitamin supplements, evening primrose oil, and aroma therapy. Because many other types of therapies are not backed by clinical trials, they may or may not be effective for regrowing hair. In fact, some may in fact make loss of hair worse. Furthermore, just because these are natural therapies does not mean that they are safe to employ. As with any therapy, it is best to discuss these methods of treatment with your doctor before you attempt to give them a try.

As well as methods of treatment to help hair grow, there are measures that can be taken to lessen the physical dangers or discomforts of lost hair.

  • Sunscreens are important for the scalp, face, and all exposed areas.

  • Spectacles (or sunglasses) protect the eyes from too much sun, and from dust and debris, when eyebrows or eyelashes are missing.

  • Hairpieces, caps, or scarves protect the scalp from sunlight and keep the head warm.

  • Antibiotic ointment applied inside the nostrils helps to protect against organisms invading the nose when nostril hair is missing.

How Will alopecia areata Affect My Life and Lifestyle?

This is a common question, particularly for children, teens and young adults who are beginning to formulate lifelong goals and who may live with the effects of pattern baldness for many years, alopecia androgenetic female. The great news is that male or female pattern baldness is not a painful ailment and does not make persons feel sick physically. It is not contagious, and individuals who have the pattern baldness affliction are generally in good health otherwise. It does not shorten life expectancy and it should not interfere with the ability to achieve such life goals as going to school, working, marrying, raising a family, playing sports, and exercising.

The psychological effects of living with baldness, however, can be a challenge. Many people cope by learning as much as they can about the disease; speaking with others who are facing the same difficulties; and, if necessary, seeking counseling to help build a positive self-image. To address quality-of-life issues for alopecia androgenetic female, male or female pattern baldness and all other skin conditions, the NIAMS sponsored a scientific meeting in September 2002 on the toll of skin conditions.

How Can I Deal With With the Effects of This Disease?

Living with hair loss can be hard, especially in a culture that sees a good head od hair as a sign of youthfulness and good health. Even so, most citizens with alopecia areata are well-adjusted, happy persons living full lives.

The key to coping is valuing yourself for who you are, not for how much hair you have or dont have. Many folks learning to deal with pattern baldness find it helpful to talk with other individuals who are dealing with the same problems. More than 4 million citizens nationwide have this disease at some point in their lives, so you are not in isolation. If you would like to be in touch with others with the condition, the National male or female pattern baldness Foundation (NAAF) can assist through its pen pal program, message boards, annual conference, and support groups that meet in several situations nationally.

Another way to deal with the ailment is to minimize its effects on your appearance. If you happen to have total alopecia, a wig or hairpiece can look natural and contemporary. For small patches of loss of hair, a hair-colored crayon, cream or powder applied to the scalp can make alopecia less obvious by eliminating the contrast between the hair and the scalp. Skilfully applied alopecia androgenetic female eyebrow pencil can mask missing eyebrows. Children with alopecia areata may prefer to wear bandanas, scarves or caps. There are many styles available to suit a child's interest and mood - some even have ponytails fixed on to them with alopecia androgenetic female.

For females, attractive scarves can hide patchy hair loss; jewelry and clothing can distract attention from patchy hair; and proper makeup can camouflage the effects of lost facial hair. If you would like to learn more about covering up the cosmetic aspects of alopecia androgenetic female male or female pattern baldness, ask your MD or members of your local support group to recommend a cosmetic professional who specializes in working with persons whose appearance is affected by medical conditions.

Is Research Close to Finding Better Treatments or a Cure?

While a cure is not imminent, researchers into hair disease are making headway toward a better understanding of the affliction. This increased understanding will likely lead the way to better treatments for pattern baldness and ultimately a way to prevent or even cure it.

Alopecia research ranges from the most basic studies of the mechanisms of hair growth and baldness in mice to testing drugs and ways to apply drugs to help regrow hair in individuals. Both the National Institutes of Health and the National male or female pattern baldness Foundation support research into the alopecia androgenetic female pattern baldness disease and its treatment. Here are some areas of research that hold promise:

  • Developing an animal model - This is a critical first step toward understanding the ailment, and much progress has been made. By developing a mouse with a affliction similar to human alopecia areata, hair research scientists hope to learn more with reference to the mechanism of the condition and eventually develop immune system methods of treatment for the condition in people.

  • Mapping genes - Researchers are studying the possible genetic causes and mechanism of the affliction both in families that have one or more persons with the ]disease] and in the general population. An understanding of the genetics of the ailment will aid in disease prevention, early intervention, and development of specific therapies.

  • Studying hair follicle development - By investigating how hair follicles form in mouse embryos, scientists hope to gain a better understanding of hair cycle biology that may lead to treatments for the underlying disease process.

  • Targeting the immune system - Several new media found to be effective in treating psoriasis may prove to be effective in alopecia androgenetic female pattern baldness. These medications work by stopping certain chemical messengers that have a role to play in the immune response, or by interfering with the activity of white blood cells (called T-cells) that are involved in the immune system's assault on hair follicles. New treatments for other autoimmune diseases like rheumatoid arthritis and lupus may also benefit patients with alopecia androgenetic female alopecia areata.

  • Finding better ways to give out drugs - One limitation of current topical therapies is getting the drug to the source of the symptoms, alopecia androgenetic female. Researchers into hair disease are looking for a substance that penetrates the fat under the skin to deliver medication directly to hair follicles. In laboratory animals, topically applied synthetic sacs known as liposomes seem to fill the bill. Studies are still appropriate to show whether liposomes achieve the same results for folks.

  • Understanding cytokines - Chemical messengers known as cytokines (alopecia androgenetic female) play a role in regulating the body's immune response, whether it is the standard response to a foreign invader such a virus or an unusual response to a part of the body. Researchers believe that by giving certain cytokines that inhibit inflammation, they may be able to slow down or stop the body's abnormal response to the hair follicles. Because giving the cytokines (alopecia androgenetic female) systemically may cause adverse effects, they believe a topical medication using liposomes to get the agents to the root of the hair inside the follicle may be more desirable.

  • Understanding stem cell biology - Epithelial stem cells are immature cells that are responsible for regenerating and maintaining a variety of tissues, including the skin and the hair follicles. Stem cells in the follicle seem to be spared from injury in male or female pattern baldness, which may explain why the potential for regrowth is always there in individuals that have the condition. By studying the biology of these cells, and their immediate offspring, which seem to be targeted by the immune system, Researchers hope to gain a better understanding of factors that trigger the ailment.

As a footnote, pattern baldness has millions of suffers worldwide - you are not alone if you also suffer from it. Bear in mind that many people adversely affect their lives in a negative way by focussing on the disease when perhaps they should be concentrating on their lives instead. The majority of people that you meet will judge you by your attitude, your personality and your general demeanor - not by the amount of hair you have on your head.

This has been a long alopecia androgenetic female article and we sincerely trust that you have found benefit in it. We would like to thank the website Hair Loss Secrets for kindly allowing us to reproduce it.

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